GMP manufacture of microfluidized and spray dried formulations for poorly soluble APIs
We develop a range of formulations for poorly soluble drug substance in order to enhance bioavailability. One such method is to make microfluidized formulations in order to reduce the particle size to micron or sub micron levels.
These very small particles have dissolution rates that are orders of magnitude faster than conventional size particles. The microfluidized material is then spray dried, also by us to GMP, and then filled into a capsule or included in a tablet formulation.
The full process from start to finish, including formulation development, analytical, physical characterisation, and GMP manufacture are carried out by our team on site at our facility in Reading UK.