Pharmaterials Ltd The Queen's Awards for Enterprise 2008
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Home | COMPANY    |     POLYMORPHS/SALTS/CO-CRYSTALS    |     FORMULATION DEVELOPMENT    |     CONSULTANCY    |     GMP MANUFACTURE    |     PHYS PROPS    |     INHALATION SERVICES    |    
Formulation Development
Preclinical Formulation Clinical Formulation Solid Oral Dosage Amorphous Solid Dispersions MacroSOLV Formulation Screening Inhaled / Respiratory Drug Delivery: Inhalation product development First time in human fast Analytical Development Excipient compatibility testing Drug Delivery Licensing Quality by Design in Formulation Development

Preclinical Formulation

The first (pre-clinical) formulation effort for a new API will usually be to prepare a solution formulation for IV administration as part of a toxicity test. Poorly soluble compounds present significant challenges in this respect.

There are a number of pre-clinical formulation strategies available and Pharmaterials has helped many companies in this phase of work. We will assess:

  • The effect of pH
  • Co-solvents
  • Surfactants
  • Cyclodextrin inclusion complex formation
  • Lipid based formulations

We are able to screen these different options rapidly using our  MacroSOLV® formulation technologies to facilitate the pre-clinical development of poorly soluble drugs.

Contact us

Experience - scientific knowledge - understanding your needs.  We will rapidly provide formulations that are designed to meet you needs.

Pharmaterials: accelerating the development of tomorrow's medicines

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