Preclinical Formulation
The first (pre-clinical) formulation effort for a new API will usually be to prepare a solution formulation for IV administration as part of a toxicity test. Poorly soluble compounds present significant challenges in this respect.
There are a number of pre-clinical formulation strategies available and Pharmaterials has helped many companies in this phase of work. We will assess:
We are able to screen these different options rapidly using our MacroSOLV® formulation technologies to facilitate the pre-clinical development of poorly soluble drugs.
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