Controlled Release
Controlled release of the active ingredient from the formulation vehicle can often be achieved through the inclusion of simple or complex polymer coatings and matrix systems. However, small changes in the formulation make up, such as polymer grade etc, can often result in great variability of the product performance compared to the original form
Our combination of high resolution imaging and chemical spectroscopy techniques can rapidly assist in the development and protection of optimised processing parameters, reducing the chances of late stage product failure and time wasted identifying the cause.
Types of analysis include:
- Chemical identification of components
- Spatial mapping & quantification of components
- Film coating integrity & thickness determination
- Identification of component migration/segregation & contamination
- In-situ identification of drug form within polymer matrices
- Identification of polymer & drug degradation
|