Formulation Development

Pharmaterials have great experience in formulation of poorly soluble drug substances for oral, IV and inhaled routes of delivery.  Approximately 60% of all new chemical entities coming from the discovery phases are poorly bioavailable, leading to many potentially innovative drug candidates being abandoned due to poor pharmacokinetic properties (such as poor water solubility or poor intestinal permeability). At Pharmaterials, our expertise is in finding formulation solutions to rescue such challenging compounds.

We have developed several drug delivery technologies to enable us to act on low solubility and/or low permeability drugs. Through our experience our team of formulators advise our clients as to the risks, timelines and expenses related to progressing their compounds in order to develop a viable and cost effective formulation.

Each formulation is designed around the physicochemical properties of the molecule in question and also on the dosage form desired. For more information on how Pharmaterials can assist with your company's own product development, please view the rest of this section.