Solid Dosage Forms 

In most cases, failure in final product stability, dissolution and bioavailability can be in part correlated back to changes in the physicochemical properties of the API and formulation components as a result of physical processing or unsuitable manufacturing procedures.

At Pharmaterials, we have the experience and technology to rapidly understand the complexity of the whole dosage form to gain greater fundamental understanding of batch to batch variability, unexpected drug release profiles and failure during stability trials.

Types of analysis include:

Spatial mapping & identification of individual components  (Chemical imaging)

Localised quantification

In-situ identification of polymorphic form and/or polymorphic form changes

In-situ assessment of interaction & degradation

Identification of component migration/segregation & contamination