Physical Characterisation Techniques

Pharmaterials has a wide range of instrumentation including inverse gas chromatography (IGC), thermal analysis (Hyper-DSC, isothermal calorimetry, solution calorimetry, high sensitivity DSC), confocal Raman mapping, DVS,  X-ray diffraction, surface area, particle sizing and many more.  Some examples are listed below:

Diffraction Studies

X-ray powder diffraction including sector leading transmission plate reading capability, single crystal X-ray for structure resolution

Thermal Methods

DSC, Hyper-DSC, TGA, Isothermal nanocalorimetry, Solution calorimetry, High sensitivity scanning calorimetry. DSC-Raman, DSC-NIR.

Microscopy

Optical, Raman, SEM, Hot-stage

Sorption/Desorption Studies

Water and organic vapour (coupled NIR probe), Nitrogen BET

Powder Surface Characterisation

Inverse gas chromatography, Confocal Raman spectroscopy

Bulk Properties Determination

Specific surface area, porosity, bulk and tapped density, powder flow

Dissolution Testing

Intrinsic and non-intrinsic methods, USP Apparatus 4 flow through dissolution testing, HPLC, UV, ELSD analysis

Chromatography

HPLC-UV/ELSD